With constantly emerging new injectable treatments in the market and the list of FDA-approved applications expanding, it has become increasingly crucial for every neurotoxin and dermal filler to distinguish itself from the others. One effective approach? Prolong its lifespan. If you have ever contemplated how to make Botox last longer or sought methods to extend the effects of Juvéderm injections, you are by no means alone.
The duration of neurotoxins' efficacy is even more significant considering the recent introduction of Daxxify, a neuromodulator freshly approved by the FDA and capable of lasting an average of six months. This implies that existing wrinkle reducers with shorter-lasting outcomes (averaging three to four months) will encounter difficulties in competing.
Fortunately, Dysport was forward-thinking. Here's how to make Dysport persist longer to obtain the greatest value for your money.
How long does Dysport last ?
Back in 2024, Galderma disclosed the results of a study on Dysport, a prominent wrinkle reducer and one of the main rivals of Botox; similar to other neuromodulators, it employs botulinum toxin to temporarily immobilize the facial muscles, smoothing dynamic wrinkles in the treated regions. The Phase 2 study examined the influence of dose escalation on the duration, effectiveness, and safety of Dysport – essentially, what occurs when a single dose of the product is more concentrated and less diluted.
Every neurotoxin is diluted, typically with saline, before injection to meet the proportions stipulated by the manufacturer. According to the FDA, for instance, each 500-unit vial of Dysport is to be diluted with 2.5 mL of sodium chloride before injection, while 300-unit vials are to be diluted with 1.5 mL of sodium chloride. However, in this study, the product was less diluted, thus containing a higher concentration of neurotoxin in each injection. A total of 401 subjects, all within the age range of 18 to 65, participated in the randomized, double-blind study, with 75% of the patients in one test group receiving a single dose of Dysport and the remaining 25% receiving a placebo.
The participants in the study were monitored for nine months to assess the efficacy of the more concentrated injection in treating the glabellar lines between the eyebrows. As anticipated, those who received Dysport treatments expressed greater satisfaction with the improvement of fine lines in the treatment areas compared to patients who received the placebo, without any additional recovery time.
But interestingly, the findings also revealed that the higher concentration of the product had a more prolonged effect than the usual concentration, with participants still observing results at the nine-month mark – which is notable as it was previously believed to last four to five months. “We are encouraged that these study results indicate that a single dose of Dysport has a rapid onset and long-lasting effect and is well tolerated,” Dr. John H. Joseph, a board-certified plastic surgeon from Beverly Hills, California, and the investigator of the study, stated in a press release. Botox and Xeomin have also undergone comparable successful trials, demonstrating that a more concentrated dose leads to longer-lasting outcomes.
This could ultimately influence consumers' expenditures. If medical providers take notice of Galderma's findings and dilute Dysport less, it is likely to result in a higher cost for patients as they would be receiving more of the actual product. Nevertheless, longer-lasting results would also likely mean that patients would not need to visit as frequently for maintenance and follow-up injections. Just like any cosmetic treatment, what works for one person might not be the ideal choice for another. A variety of factors – including metabolism, the desired degree of muscle mobility, and accumulated immunity resistance – can play a role in selecting the most suitable toxin for your requirements.
How to make Dysport last longer
There is no miraculous technique to make treatments like Dysport and Botox last longer. However, since these neurotoxins ostensibly aim to improve fine lines and wrinkles, it can be beneficial to avoid anything that accelerates the aging process – such as, for example, sun damage, which is accountable for approximately 80% of the visible signs of aging.
A diligent anti-aging skincare routine, which incorporates the use of a broad-spectrum sunscreen with at least SPF 30 – which is the minimum amount recommended by the American Academy of Dermatology – is an obvious choice for maintaining excellent results from Dysport.
It is also essential to hydrate and moisturize the skin, as it loses moisture with age; humectants, like hyaluronic acid, can also plump the skin instantly. Retinol is another favorable option as it stimulates collagen production – which in turn can keep the skin smooth, firm, and wrinkle-free. (Just be sure to use appropriate sun protection, as retinol increases the skin's sensitivity to sun exposure.)
Research also indicates that an oral zinc supplement can extend the lifespan of Dysport and Botox injections by nearly 30%. (As always, consult your doctor before introducing any new supplements.)
Last but not least: you should only consult an experienced injector, such as a board-certified dermatologist, to guarantee you obtain the best possible – and longest-lasting – Dysport and Botox results.
Related: Botox, Dysport, Xeomin, or Jeuveau: What’s the Difference?
