Hypopigmentation (lighter skin coloring) is not a common side effect of Oratane (Isotretinoin), although in my experience, I have noted lightening of lip color in patients with darker skin tones. While acne requires a comprehensive approach for long-term improvement, it is crucial to use a combination of skincare products while on Isotretinoin. These include vitamin C, glycolic cream, kojic acid serums, and hyaluronic acid serum in the morning, as well as retinols, salicylic acid, growth factors, and peptides at night. Additionally, incorporating non-ablative laser treatments, microneedling with PRP or RF, LED light therapy, and peels can further enhance the outcomes while on oral acne medications. I suggest consulting with an expert who combines skincare, lasers, microneedling, PRP, and facials for acne treatment while on Isotretinoin. Best regards.
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